Inclusion of Smoking Data in Cardiovascular Disease Risk Estimation. | Vanderbilt Center for Clinical Cardiovascular Outcomes Research and Trials Evaluation

Duncan MS, Greevy RA, Tindle HA, Vasan RS, Lipworth L, Aldrich MC, Lloyd-Jones DM, Freiberg MS. Inclusion of Smoking Data in Cardiovascular Disease Risk Estimation. JAMA cardiology. 2022 Feb 1;7(7). 195-203. PMID: 34878493 [PubMed] PMCID: PMC8655664

Abstract

Former heavy smokers (ie, those with ≥20 pack-years of smoking) may have higher atherosclerotic cardiovascular disease (ASCVD) risk than never smokers for up to 16 years after smoking cessation. However, the 2013 pooled cohort equations (PCE) do not account for pack-years of smoking and only consider current vs noncurrent smoking status without distinguishing former smokers from never smokers.